When Antibiotics Fail

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When Antibiotics Fail

When Antibiotics Fail [Pdf/ePub] eBook ISBN-10: 1926522753
Publisher: Council of Canadian Academies
File Size: 549 KB
File Format: Pdf
Read Count: 2977142


When Antibiotics Fail by Book Resume:

When Antibiotics Fail examines the current impacts of AMR on our healthcare system, projects the future impact on Canada’s GDP, and looks at how widespread resistance will influence the day-to-day lives of Canadians. The report examines these issues through a One Health lens, recognizing the interconnected nature of AMR, from healthcare settings to the environment to the agriculture sector. It is the most comprehensive report to date on the economic impact of AMR in Canada.


Superbugs [Pdf/ePub] eBook ISBN-10: 0674985079
Author: William Hall
Publisher: Harvard University Press
File Size: 1272 KB
File Format: Pdf
Read Count: 248423


Superbugs by William Hall Book Resume:

Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading. Unnecessary use of antibiotics in both humans and animals accelerates the evolution of drug-resistant bacteria, with potentially catastrophic personal and global consequences. Our best defenses against infectious disease could cease to work, surgical procedures would become deadly, and we might return to a world where even small cuts are life-threatening. The problem of drug resistance already kills over one million people across the world every year and has huge economic costs. Without action, this problem will become significantly worse. Following from their work on the Review on Antimicrobial Resistance, William Hall, Anthony McDonnell, and Jim O’Neill outline the major systematic failures that have led to this growing crisis. They also provide a set of solutions to tackle these global issues that governments, industry, and public health specialists can adopt. In addition to personal behavioral modifications, such as better handwashing regimens, Superbugs argues for mounting an offense against this threat through agricultural policy changes, an industrial research stimulus, and other broad-scale economic and social incentives.

The Resistance Phenomenon in Microbes and Infectious Disease Vectors

The Resistance Phenomenon in Microbes and Infectious Disease Vectors [Pdf/ePub] eBook ISBN-10: 9780309168304
Author: Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher: National Academies Press
File Size: 1003 KB
File Format: Pdf
Read Count: 7952683


The Resistance Phenomenon in Microbes and Infectious Disease Vectors by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Book Resume:

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Antibiotic Resistance

Antibiotic Resistance [Pdf/ePub] eBook ISBN-10: 9780309185349
Author: Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher: National Academies Press
File Size: 388 KB
File Format: Pdf
Read Count: 3545180


Antibiotic Resistance by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Book Resume:

Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antibiotics and Bacterial Resistance

Antibiotics and Bacterial Resistance [Pdf/ePub] eBook ISBN-10: 1118580915
Author: Wiley
Publisher: John Wiley & Sons
File Size: 974 KB
File Format: Pdf
Read Count: 5127573


Antibiotics and Bacterial Resistance by Wiley Book Resume:

The need for novel antibiotics is greater now than perhaps anytime since the pre-antibiotic era. Indeed, the recent collapse ofmany pharmaceutical antibacterial groups, combined with theemergence of hypervirulent and pan-antibiotic-resistant bacteriahas severely compromised infection treatment options and led todramatic increases in the incidence and severity of bacterialinfections. This collection of reviews and laboratory protocols gives thereader an introduction to the causes of antibiotic resistance, thebacterial strains that pose the largest danger to humans (i.e.,streptococci, pneumococci and enterococci) and the antimicrobialagents used to combat infections with these organisms. Some newavenues that are being investigated for antibiotic development arealso discussed. Such developments include the discovery of agentsthat inhibit bacterial RNA degradation, the bacterial ribosome, andstructure-based approaches to antibiotic drug discovery. Two laboratory protocols are provided to illustrate differentstrategies for discovering new antibiotics. One is a bacterialgrowth inhibition assay to identify inhibitors of bacterial growththat specifically target conditionally essential enzymes in thepathway of interest. The other protocol is used to identifyinhibitors of bacterial cell-to-cell signaling. This e-book — a curated collection from eLS, WIREs, andCurrent Protocols — offers a fantastic introduction to thefield of antibiotics and antibiotic resistance for students orinterdisciplinary collaborators. Table of Contents: Introduction Antibiotics and the Evolution of Antibiotic Resistance eLS Jose L Martinez, Fernando Baquero Antimicrobials Against Streptococci, Pneumococci andEnterococci eLS Susan Donabedian, Adenike Shoyinka Techniques & Applications RNA decay: a novel therapeutic target in bacteria WIREs RNA Tess M. Eidem, Christelle M. Roux, Paul M. Dunman Antibiotics that target protein synthesis WIREs RNA Lisa S. McCoy, Yun Xie, Yitzhak Tor Methods High-Throughput Assessment of Bacterial Growth Inhibition byOptical Density Measurements Current Protocols Chemical Biology Jennifer Campbell Structure-Based Approaches to Antibiotic Drug Discovery Current Protocols Microbiology George Nicola, Ruben Abagyan Novel Approaches to Bacterial Infection Therapy by Interferingwith Cell-to-Cell Signaling Current Protocols Microbiology David A. Rasko, Vanessa Sperandio

The Use of Drugs in Food Animals

The Use of Drugs in Food Animals [Pdf/ePub] eBook ISBN-10: 9780309175777
Author: National Research Council,Board on Agriculture,Panel on Animal Health, Food Safety, and Public Health,Committee on Drug Use in Food Animals
Publisher: National Academies Press
File Size: 1908 KB
File Format: Pdf
Read Count: 8202514


The Use of Drugs in Food Animals by National Research Council,Board on Agriculture,Panel on Animal Health, Food Safety, and Public Health,Committee on Drug Use in Food Animals Book Resume:

The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industries--poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management. November

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses [Pdf/ePub] eBook ISBN-10: 1108864120
Author: OECD,World Health Organization
Publisher: OECD Publishing
File Size: 1616 KB
File Format: Pdf
Read Count: 4350597


Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses by OECD,World Health Organization Book Resume:

Antimicrobial resistance (AMR) is a biological mechanism whereby a microorganism evolves over time to develop the ability to become resistant to antimicrobial therapies such as antibiotics. The drivers of and potential solutions to AMR are complex, often spanning multiple sectors. The internationally recognized response to AMR advocates for a ‘One Health’ approach, which requires policies to be developed and implemented across human, animal, and environmental health.

The Perfect Predator

The Perfect Predator [Pdf/ePub] eBook ISBN-10: 0316418072
Author: Steffanie Strathdee,Thomas Patterson
Publisher: Hachette Books
File Size: 1203 KB
File Format: Pdf
Read Count: 7780021


The Perfect Predator by Steffanie Strathdee,Thomas Patterson Book Resume:

An electrifying memoir of one woman's extraordinary effort to save her husband's life-and the discovery of a forgotten cure that has the potential to save millions more. "A memoir that reads like a thriller." -New York Times Book Review "A fascinating and terrifying peek into the devastating outcomes of antibiotic misuse-and what happens when standard health care falls short." -Scientific American Epidemiologist Steffanie Strathdee and her husband, psychologist Tom Patterson, were vacationing in Egypt when Tom came down with a stomach bug. What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world. Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure. A nail-biting medical mystery, The Perfect Predator is a story of love and survival against all odds, and the (re)discovery of a powerful new weapon in the global superbug crisis.

Antibiotic Discovery and Development

Antibiotic Discovery and Development [Pdf/ePub] eBook ISBN-10: 1461414008
Author: Thomas J. Dougherty,Michael J. Pucci
Publisher: Springer Science & Business Media
File Size: 1158 KB
File Format: Pdf
Read Count: 2125651


Antibiotic Discovery and Development by Thomas J. Dougherty,Michael J. Pucci Book Resume:

This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.


Superbugs [Pdf/ePub] eBook ISBN-10: 0735217521
Author: Matt McCarthy
Publisher: Penguin
File Size: 1043 KB
File Format: Pdf
Read Count: 478550


Superbugs by Matt McCarthy Book Resume:

International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?

Biography of Resistance

Biography of Resistance [Pdf/ePub] eBook ISBN-10: 0062862987
Author: Muhammad H. Zaman
Publisher: HarperCollins
File Size: 1162 KB
File Format: Pdf
Read Count: 2861337


Biography of Resistance by Muhammad H. Zaman Book Resume:

Award-winning Boston University educator and researcher Muhammad H. Zaman provides a chilling look at the rise of antibiotic-resistant superbugs, explaining how we got here and what we must do to address this growing global health crisis. In September 2016, a woman in Nevada became the first known case in the U.S. of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions. “It will be like the great plague of the middle ages, the influenza pandemic of 1918, the AIDS crisis of the 1990s, and the Ebola epidemic of 2014 all combined into a single threat,” Muhammad H. Zaman warns. The Biography of Resistance is Zaman’s riveting and timely look at why and how microbes are becoming superbugs. It is a story of science and evolution that looks to history, culture, attitudes and our own individual choices and collective human behavior. Following the trail of resistant bacteria from previously uncontacted tribes in the Amazon to the isolated islands in the Arctic, from the urban slums of Karachi to the wilderness of the Australian outback, Zaman examines the myriad factors contributing to this unfolding health crisis—including war, greed, natural disasters, and germophobia—to the culprits driving it: pharmaceutical companies, farmers, industrialists, doctors, governments, and ordinary people, all whose choices are pushing us closer to catastrophe. Joining the ranks of acclaimed works like Microbe Hunters, The Emperor of All Maladies, and Spillover, A Biography of Resistance is a riveting and chilling tale from a natural storyteller on the front lines, and a clarion call to address the biggest public health threat of our time.

Tackling Antimicrobial Use and Resistance in Pig Production

Tackling Antimicrobial Use and Resistance in Pig Production [Pdf/ePub] eBook ISBN-10: 9210041577
Author: Food and Agriculture Organization (FAO)
Publisher: United Nations
File Size: 1080 KB
File Format: Pdf
Read Count: 8295947


Tackling Antimicrobial Use and Resistance in Pig Production by Food and Agriculture Organization (FAO) Book Resume:

This report describes a campaign to limit the use of antimicrobials – specifically antibiotics – in the Danish swine-producing sector. It is a testimony of the collaboration between the regulatory sector within the Ministry of Environment and Food (and its agriculture-focused precursors), private veterinary practitioners and swine producers (large and small), to tackle the unsustainable overuse of antibiotics in the industry, and is a retrospective tribute to all those who had the foresight to make significant changes to ensure consumer protection: improving hygiene at primary sites of swine production, developing options for intervention through a system of surveillance and collation of data from feed mills to veterinary practitioner prescriptions, identifying sites for intervention, setting targets, restructuring the relationship between the veterinary services and farmers, and implementing changes in behaviour for greatest impact. Denmark in many ways laid out a plan before there was any known roadmap to follow; each step was based on continuous analysis and feedback to the operators – private and public – for ongoing monitoring and accountability as a driver for change. It is hoped that this historical guide may serve other countries, food producers, regulators, veterinarians and those responsible for veterinary structures, as well as academia, to identify ways forward to limit the emergence and spread of antimicrobial resistance, which is threatening public health, animal health and safe food production worldwide.

Technological Challenges in Antibiotic Discovery and Development

Technological Challenges in Antibiotic Discovery and Development [Pdf/ePub] eBook ISBN-10: 0309298172
Author: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable
Publisher: National Academies Press
File Size: 1493 KB
File Format: Pdf
Read Count: 9353809


Technological Challenges in Antibiotic Discovery and Development by National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Chemical Sciences Roundtable Book Resume:

Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.

Antibiotic Resistance

Antibiotic Resistance [Pdf/ePub] eBook ISBN-10: 9780132117326
Author: Karl S. Drlica,David S. Perlin
Publisher: FT Press
File Size: 1849 KB
File Format: Pdf
Read Count: 9065718


Antibiotic Resistance by Karl S. Drlica,David S. Perlin Book Resume:

Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

Antimicrobial Resistance

Antimicrobial Resistance [Pdf/ePub] eBook ISBN-10: 030959183X
Author: Forum on Emerging Infections,Institute of Medicine
Publisher: National Academies Press
File Size: 1004 KB
File Format: Pdf
Read Count: 877198


Antimicrobial Resistance by Forum on Emerging Infections,Institute of Medicine Book Resume:

Antibiotic resistance is neither a surprising nor a new phenomenon. It is an increasingly worrisome situation, however, because resistance is growing and accelerating while the world's tools for combating it decrease in power and number. In addition, the cost of the problem--especially of multidrug resistance--in terms of money, mortality, and disability are also rising. This book summarizes a workshop on antimicrobial resistance held by the Forum on Emerging Infections. The goal of the Forum on Emerging Infections is to provide an opportunity for representatives of academia, industry, government, and professional and interest groups to examine and discuss scientific and policy dilemmas of common interest that are specifically related to research on and the prevention, detection, and management of emerging infections. Organized as a topic-by-topic synthesis of presentations and exchanges during the workshop, the book highlights lessons learned, delineates a range of pivotal issues and the problems they raise, and proposes some simplified ideas about possible responses.

The Antibiotic Paradox

The Antibiotic Paradox [Pdf/ePub] eBook ISBN-10: 1489960422
Author: Stuart B. Levy
Publisher: Springer
File Size: 389 KB
File Format: Pdf
Read Count: 8820870


The Antibiotic Paradox by Stuart B. Levy Book Resume:

The discovery of antibiotics heralded medicine's triumph over previously fatal diseases that once destroyed entire civilizations - thus earning their reputation as miracle drugs. But today, the terrifying reality of antibiotic-resistant bacteria resulting from our widespread misuse of antibiotics forewarns us that the miracle may be coming to an end. The seemingly innocent consumer who demands antibiotics to treat nonbacterial diseases such as the common cold or plays doctor by saving old prescriptions for later use is paving the way for a future of antibiotic failure. "What harm can it do?" is a popular refrain of people worldwide as they pop another antibiotic pill. Dr. Stuart Levy - the leading international expert on hazards of antibiotic misuse - reveals how this cavalier and naive attitude about the power of antibiotics can have deadly consequences. He explains that we are presently witnessing a massive evolutionary change in bacteria. This build-up of new antibiotic-resistant bacteria in individuals and the environment worldwide is an insidious and silent process. Thus, unwittingly consumers encounter resistant bacteria in their meat, poultry, fish, and vegetables. Unregulated dispensing of antibiotics in poorer countries breeds countless more resistant strains. Since bacteria recognize no geographical boundaries, resistant forms can travel the globe. If this trend continues to grow unchecked, we may someday find that all of our antibiotics are obsolete. Today doctors can no longer expect that their first choice of antibiotic for women's urinary tract infections or children's ear infections will work. Similarly, cancer therapy is rendered useless if patients are unable to fight infections that are sometimes resistant to eight to ten different drugs. In developing countries, people are now dying of previously treatable diseases that are no longer responsive to traditional antibiotics. These problems are just a harbinger of what will come if we do not act now. Dr. Levy, recognized by The New Yorker for his superb contributions to this field, is sending out an urgent message that the world cannot afford to ignore any longer. The goal of this unprecedented investigation into the dangers of antibiotic misuse is to protect the world community from resistant infections and ensure the success of antibiotics for generations to come

CDC Yellow Book 2018: Health Information for International Travel

CDC Yellow Book 2018: Health Information for International Travel [Pdf/ePub] eBook ISBN-10: 0190628634
Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
File Size: 1643 KB
File Format: Pdf
Read Count: 8919231


CDC Yellow Book 2018: Health Information for International Travel by Centers for Disease Control and Prevention CDC Book Resume:

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Management of Antimicrobials in Infectious Diseases

Management of Antimicrobials in Infectious Diseases [Pdf/ePub] eBook ISBN-10: 1603272399
Author: Arch G. Mainous III,Claire Pomeroy
Publisher: Springer Science & Business Media
File Size: 1630 KB
File Format: Pdf
Read Count: 7702266


Management of Antimicrobials in Infectious Diseases by Arch G. Mainous III,Claire Pomeroy Book Resume:

Recent evidence suggests an increasing rate of antimicrobial resistant pathogens throughout the world. Pathogens like Staphylococcus aureus are showing substantial prevalence of resistance to antibiotics. Thus, we think that given these developments, clinicians would welcome an updated version of this book. A resource indicating appropriate, evidence-based antimicrobial treatment of infectious diseases encountered in both the hospital and outpatient settings would be of significant value to practicing clinicians. The book would focus on the clinical importance of appropriate diagnosis and treatment of infectious diseases particularly in terms of antibiotic-resistance. The resource would be valuable to countless numbers of junior-level practitioners (residents, nurse practitioners, physician-assistants). Moreover, the book could be a resource for generalists as well as infectious disease specialists.


Superbug [Pdf/ePub] eBook ISBN-10: 9781439171837
Author: Maryn McKenna
Publisher: Simon and Schuster
File Size: 1729 KB
File Format: Pdf
Read Count: 3370336


Superbug by Maryn McKenna Book Resume:

LURKING in our homes, hospitals, schools, and farms is a terrifying pathogen that is evolving faster than the medical community can track it or drug developers can create antibiotics to quell it. That pathogen is MRSA—methicillin-resistant Staphyloccocus aureus—and Superbug is the first book to tell the story of its shocking spread and the alarming danger it poses to us all. Doctors long thought that MRSA was confined to hospitals and clinics, infecting almost exclusively those who were either already ill or old. But through remarkable reporting, including hundreds of interviews with the leading researchers and doctors tracking the deadly bacterium, acclaimed science journalist Maryn McKenna reveals the hidden history of MRSA’s relentless advance—how it has overwhelmed hospitals, assaulted families, and infiltrated agriculture and livestock, moving inexorably into the food chain. Taking readers into the medical centers where frustrated physicians must discard drug after drug as they struggle to keep patients alive, she discloses an explosion of cases that demonstrate how MRSA is growing more virulent, while evolving resistance to antibiotics with astonishing speed. It may infect us at any time, no matter how healthy we are; it is carried by a stunning number of our household pets; and it has been detected in food animals from cows to chickens to pigs. With the sensitivity of a novelist, McKenna portrays the emotional and financial devastation endured by MRSA’s victims, vividly describing the many stealthy ways in which the pathogen overtakes the body and the shock and grief of parents whose healthy children were felled by infection in just hours. Through dogged detective work, she discloses the unheard warnings that predicted the current crisis and lays bare the flaws that have allowed MRSA to rage out of control: misplaced government spending, inadequate public health surveillance, misguided agricultural practices, and vast overuse of the few precious drugs we have left. Empowering readers with the knowledge they need for self-defense, Superbug sounds an alarm: MRSA has evolved into a global emergency that touches almost every aspect of modern life. It is, as one deeply concerned researcher tells McKenna, "the biggest thing since AIDS."


Meltdown [Pdf/ePub] eBook ISBN-10: 0735233330
Author: Chris Clearfield,András Tilcsik
Publisher: Penguin
File Size: 573 KB
File Format: Pdf
Read Count: 8690824


Meltdown by Chris Clearfield,András Tilcsik Book Resume:

Winner of the 2019 National Business Book Award A groundbreaking take on how complexity causes failure in all kinds of modern systems—from social media to air travel—this practical and entertaining book reveals how we can prevent meltdowns in business and life. A crash on the Washington, D.C. metro system. An accidental overdose in a state-of-the-art hospital. An overcooked holiday meal. At first glance, these disasters seem to have little in common. But surprising new research shows that all these events—and the myriad failures that dominate headlines every day—share similar causes. By understanding what lies behind these failures, we can design better systems, make our teams more productive, and transform how we make decisions at work and at home. Weaving together cutting-edge social science with riveting stories that take us from the frontlines of the Volkswagen scandal to backstage at the Oscars, and from deep beneath the Gulf of Mexico to the top of Mount Everest, Chris Clearfield and András Tilcsik explain how the increasing complexity of our systems creates conditions ripe for failure and why our brains and teams can't keep up. They highlight the paradox of progress: Though modern systems have given us new capabilities, they've become vulnerable to surprising meltdowns—and even to corruption and misconduct. But Meltdown isn't just about failure; it's about solutions—whether you're managing a team or the chaos of your family's morning routine. It reveals why ugly designs make us safer, how a five-minute exercise can prevent billion-dollar catastrophes, why teams with fewer experts are better at managing risk, and why diversity is one of our best safeguards against failure. The result is an eye-opening, empowering, and entirely original book—one that will change the way you see our complex world and your own place in it.

Viruses Vs. Superbugs

Viruses Vs. Superbugs [Pdf/ePub] eBook ISBN-10: 0230552285
Author: T. Häusler,Thomas Häusler
Publisher: Springer
File Size: 1966 KB
File Format: Pdf
Read Count: 7666655


Viruses Vs. Superbugs by T. Häusler,Thomas Häusler Book Resume:

Each year thousands of people die from bacteria resistant to antibiotics. Alternative drugs are urgently needed. A surprising ray of hope from the past are viruses that kill bacteria, but not us. Award-winning science journalist Thomas Häusler investigates how these long-forgotten cures may help sick people today.

The Drugs Don't Work

The Drugs Don't Work [Pdf/ePub] eBook ISBN-10: 0241968887
Author: Professor Dame Sally Davies,Jonathan Grant,Mike Catchpole
Publisher: Penguin UK
File Size: 470 KB
File Format: Pdf
Read Count: 7107808


The Drugs Don't Work by Professor Dame Sally Davies,Jonathan Grant,Mike Catchpole Book Resume:

The Drugs Don't Work - A Penguin Special by Professor Dame Sally Davies, the Chief Medical Officer for England 'If we fail to act, we are looking at an almost unthinkable scenario where antibiotics no longer work and we are cast back into the dark ages of medicine where treatable infections and injuries will kill once again' David Cameron, Prime Minister Resistance to our current range of antibiotics is the new inconvenient truth. If we don't act now, we risk the health of our parents, our children and our grandchildren. Antibiotics add, on average, twenty years to our lives. For over seventy years, since the manufacture of penicillin in 1943, we have survived extraordinary operations and life-threatening infections. We are so familiar with these wonder drugs that we take them for granted. The truth is that we have been abusing them: as patients, as doctors, as travellers, in our food. No new class of antibacterial has been discovered for twenty six years and the bugs are fighting back. If we do not take responsibility now, in a few decades we may start dying from the most commonplace of operations and ailments that can today be treated easily. This short book, which will be enjoyed by readers of An Inconvenient Truth by Al Gore and Bad Pharma by Ben Goldacre, will be the subject of a TEDex talk given by Professor Dame Sally Davies at the Royal Albert Hall. Professor Dame Sally C. Davies is the Chief Medical Officer for England and the first woman to hold the post. As CMO she is the independent advisor to the Government on medical matters with particular interest in Public Health and Research. She holds a number of international advisory positions and is an Emeritus Professor at Imperial College. Dr Jonathan Grant is a Principal Research Fellow and former President at RAND Europe, a not-for-profit public policy research institute. His main research interests are on health R&D policy and the use of research and evidence in policymaking. He was formerly Head of Policy at The Wellcome Trust. He received his PhD from the Faculty of Medicine, University of London, and his B.Sc. (Econ) from the London School of Economics. Professor Mike Catchpole is an internationally recognized expert in infectious diseases and the Director of Infectious Disease Surveillance and Control at Public Health England. He has coordinated many national infectious disease outbreak investigations and is an advisor to the European Centre for Disease Prevention and Control. He is also a visiting professor at Imperial College.

Miracle Cure

Miracle Cure [Pdf/ePub] eBook ISBN-10: 0698184106
Author: William Rosen
Publisher: Penguin
File Size: 841 KB
File Format: Pdf
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Miracle Cure by William Rosen Book Resume:

The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

Seeing Like a State

Seeing Like a State [Pdf/ePub] eBook ISBN-10: 0300252986
Author: James C. Scott
Publisher: Yale University Press
File Size: 712 KB
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Read Count: 2608006


Seeing Like a State by James C. Scott Book Resume:

“One of the most profound and illuminating studies of this century to have been published in recent decades.”—John Gray, New York Times Book Review Hailed as “a magisterial critique of top-down social planning” by the New York Times, this essential work analyzes disasters from Russia to Tanzania to uncover why states so often fail—sometimes catastrophically—in grand efforts to engineer their society or their environment, and uncovers the conditions common to all such planning disasters. “Beautifully written, this book calls into sharp relief the nature of the world we now inhabit.”—New Yorker “A tour de force.”— Charles Tilly, Columbia University

The Lost Language of Plants

The Lost Language of Plants [Pdf/ePub] eBook ISBN-10: 1603580220
Author: Stephen Harrod Buhner
Publisher: Chelsea Green Publishing
File Size: 1615 KB
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Read Count: 1809343


The Lost Language of Plants by Stephen Harrod Buhner Book Resume:

This could be the most important book you will read this year. Around the office at Chelsea Green it is referred to as the "pharmaceutical Silent Spring." Well-known author, teacher, lecturer, and herbalist Stephen Harrod Buhner has produced a book that is certain to generate controversy. It consists of three parts: A critique of technological medicine, and especially the dangers to the environment posed by pharmaceuticals and other synthetic substances that people use in connection with health care and personal body care. A new look at Gaia Theory, including an explanation that plants are the original chemistries of Gaia and those phytochemistries are the fundamental communications network for the Earth's ecosystems. Extensive documentation of how plants communicate their healing qualities to humans and other animals. Western culture has obliterated most people's capacity to perceive these messages, but this book also contains valuable information on how we can restore our faculties of perception. The book will affect readers on rational and emotional planes. It is grounded in both a New Age spiritual sensibility and hard science. While some of the author's claims may strike traditional thinkers as outlandish, Buhner presents his arguments with such authority and documentation that the scientific underpinnings, however unconventional, are completely credible. The overall impact is a powerful, eye-opening expos' of the threat that our allopathic Western medical system, in combination with our unquestioning faith in science and technology, poses to the primary life-support systems of the planet. At a time when we are preoccupied with the terrorist attacks and the possibility of biological warfare, perhaps it is time to listen to the planet. This book is essential reading for anyone concerned about the state of the environment, the state of health care, and our cultural sanity.

Biofilms in otitis

Biofilms in otitis [Pdf/ePub] eBook ISBN-10: 9062992439
Author: R. Kania,B. Ars
Publisher: Kugler Publications
File Size: 1745 KB
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Read Count: 6348337


Biofilms in otitis by R. Kania,B. Ars Book Resume:

Biofilms definitively play a role in otitis media. Biofilms are multicellular networks of bacteria encased in a matrix. Understanding the nature of the biofilm component in the pathogenesis of otitis media will likely have a meaningful influence on the development of novel strategies in the prevention and/or treatment of otitis media. This book provides an overview in addition to some new data, while simultaneously attempting to shed light on the specific mechanisms involved in middle ear pathologies. The text includes executive summaries linked to clear objectives and diagrams or figures in order to fully convey a clear and powerful message.


Obsession [Pdf/ePub] eBook ISBN-10: 0061887072
Author: Gloria Vanderbilt
Publisher: Harper Collins
File Size: 1417 KB
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Read Count: 6352816


Obsession by Gloria Vanderbilt Book Resume:

The marriages of desire . . . From the multitalented and versatile Gloria Vanderbilt comes a passionate, sensual, witty, and puzzling tale of erotic obsession, beauty, and revenge, told in tandem by two women obsessed with the same man—and, ultimately, with each other. Talbot Bingham is a renowned architectural genius who, with his formidable wife, Priscilla, creates an architectural community. When he dies unexpectedly in the middle of their tenth wedding anniversary celebration, the devastated Priscilla is left keeper of the flame of Talbot's genius. Going through her husband's archives, she comes unexpectedly upon a pile of neatly tied letters, and the shocking secret of her husband's intimate life—a discovery that shatters the foundation of her soul and spirit. Obsession explores the mysteries of the human heart and the nature of sexuality and obsession, provoking questions about whom we choose to love, and why. The reader is left to decide if the other woman represents another facet of Priscilla, or if Priscilla her-self has invented the other woman who completed the world her husband so recently inhabited?

Radical Medicine

Radical Medicine [Pdf/ePub] eBook ISBN-10: 159477935X
Author: Louisa L. Williams
Publisher: Simon and Schuster
File Size: 400 KB
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Read Count: 7414493


Radical Medicine by Louisa L. Williams Book Resume:

A “radical” approach to holistic healing that examines the root causes and cures for ailments such as Alzheimer’s disease, breast cancer, and heart attacks • Offers cutting-edge detoxification and draining therapies to address the tremendous chemical onslaught of modern life • Explains the profound health problems caused by dental amalgams, vaccinations, antibiotics, cosmetics With the historic use of toxic mercury amalgam fillings, excessive courses of antibiotics, damaging childhood vaccines, and the many industrial pollutants and chemicals that have been spread into our air, water, and food over the past century, general holistic health guidelines are simply no longer adequate for most people. Only through radical measures--that is, getting to the true root or underlying cause of disease--can effective healing occur. In Radical Medicine, naturopathic physician Louisa Williams describes how to treat these and other modern-day “obstacles to cure,” in order to ensure against future degenerative disease and achieve the optimal health that is our birthright. Examining the many health problems triggered by dental amalgams and poor dentistry, Dr. Williams explains that our teeth are focal points for health issues that arise elsewhere in the body. She explores the impact of vaccinations, the excessive use of antibiotics, and the chemical-laden products used as health and beauty aids--which are linked to Alzheimer’s disease, heart attacks, and breast and other cancers--and provides information on cutting-edge detoxification treatments as well as drainage and nutritional therapies. A practical guide for practitioners and patients alike, Radical Medicine offers a wealth of holistic, natural therapies for overcoming what is poisoning us and our world so we can achieve optimal health and well-being.

Herbal Antibiotics, 2nd Edition

Herbal Antibiotics, 2nd Edition [Pdf/ePub] eBook ISBN-10: 1603428798
Author: Stephen Harrod Buhner
Publisher: Storey Publishing
File Size: 1708 KB
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Read Count: 8501576


Herbal Antibiotics, 2nd Edition by Stephen Harrod Buhner Book Resume:

With antibiotic-resistant infections on the rise, herbal remedies present a naturally effective alternative to standard antibiotics. Herbal expert Stephen Harrod Buhner explains the roots of antibiotic resistance, explores the value of herbal treatments, and provides in-depth profiles of 30 valuable plants, noting the proper dosages, potential side effects, and contraindications of each.


Antibiotics [Pdf/ePub] eBook ISBN-10: 1608705935
Author: Kristi Lew
Publisher: Cavendish Square Publishing, LLC
File Size: 332 KB
File Format: Pdf
Read Count: 7698860


Antibiotics by Kristi Lew Book Resume:

At one time or another we've all had an infection. Maybe it was an ear infection or one from a bad scrape. Tiny living creatures called bacteria were the cause. Readers will discover what bacteria are, the discovery of antibiotics that fight bacteria off, how they work, and the future of this important medical advance.

The Power of Eucalyptus for Health & Healing

The Power of Eucalyptus for Health & Healing [Pdf/ePub] eBook ISBN-10: 1463457928
Author: Jack Malloy
Publisher: Author House
File Size: 1617 KB
File Format: Pdf
Read Count: 8916407


The Power of Eucalyptus for Health & Healing by Jack Malloy Book Resume:

Do you suffer from headaches or migraines? Are you tired of short term fixes that just address symptoms? Do back aches and sore feet keep you from living the active life you deserve? Is there an alternative to pills and surgery? Does the pain of arthritis cripple your ability to move freely? Do chronic sinus problems plagiarize you? Are you addicted to nose spray? All these problems have been prevalent throughout history and certain enlightened civilizations have successfully addressed them, and many more by using a special Eucalyptus based Liniment. This author has introduced thousands of people to the healing powers of this Liniment and many of their stories are included. Discover for yourself the power of nature’s most versatile and effective natural healing remedy. Nature’s gift of health is now, and has always been, available to everyone.

Shaman, Healer, Sage

Shaman, Healer, Sage [Pdf/ePub] eBook ISBN-10: 0307421619
Author: Alberto Villoldo, Ph.D.
Publisher: Harmony
File Size: 369 KB
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Read Count: 9225169


Shaman, Healer, Sage by Alberto Villoldo, Ph.D. Book Resume:

Alberto Villoldo, a classically trained medical anthropologist, has studied shamanic healing techniques among the descendants of the ancient Inkas for more than twenty years. In Shaman, Healer, Sage, he draws on his vast body of knowledge to create a practical and revolutionary program based on the traditional healing methods used by these shamans -- methods that, until now, have been inaccessible to most of the world. Villoldo explains that central to shamanic healing is the concept of the Luminous Energy Field that is believed to surround our material bodies. His book teaches us to see and influence the imprints that disease leaves on this field and thereby to heal ourselves and others, as well as prevent illness. Villoldo weaves wonderful teaching stories throughout about the healing power of the energy medicine of the Americas. In one story, Villoldo comes down with pneumonia while in Peru. When antibiotics fail to control the infection, his mentor, the shaman Don Antonio, uses the process of Illumination to remove the toxins that had invaded Villoldo's body. These same shamanic techniques later allowed Villoldo to remove stagnant energy from a young woman whose marriage was suffering due to her past experience with abandonment. With the aid of shamanic work, the woman regained her trust in others, and her marriage was revitalized. This book is rich with ancient wisdom and contemporary techniques we can use to help ourselves and others, as well as with the more advanced methods of master shamans, which are being brought to a wide audience for the first time.

Continual Raving

Continual Raving [Pdf/ePub] eBook ISBN-10: 0190677333
Author: Janet R. Gilsdorf
Publisher: Oxford University Press
File Size: 1820 KB
File Format: Pdf
Read Count: 4066930


Continual Raving by Janet R. Gilsdorf Book Resume:

Not all scientific discoveries are genius. Continual Raving tells the combined stories of how scientists across the 19th and 20th centuries defeated meningitis -- not through flawless scientific research, but often through a series of serendipitous events, misplaced assumptions, and flawed conclusions. The result is a story of not just a vanquished disease, but how scientific accomplishment sometimes occurs where it's least expected. Although symptoms of meningitis were recorded as early as Hippocrates and the ancient Greeks, our understanding of the disease's origins and mechanisms remained obscure for most of human history. That changed in 1892, when German physician Richard Pfeiffer observed and isolated bacteria ultimately shown to cause meningitis in children -- and concluded that those bacteria cause influenza. Haemophilus influenzae, as thee meningitis-causing bacteria have been erroneously named ever since, continued their strange journey to discovery in the decades that followed. Continual Raving traces the disease's strange encounters with science, including: · Heinrich Quincke, the German internist who first used a needle to draw spinal fluid from between a patient's back bones · Simon Flexner's management of American meningitis epidemics using immune serum from a horse · American bacteriologist Margaret Pittman's discovery (during the Great Depression, no less) of a sugar overcoat that protects the bacteria from white blood cells · Pediatrician Ashley Weech, who gave the first antibiotic used in America (based on instructions written in German) to a young patient sick with meningitis · Microbiologist Hattie Alexander, who learned why these antibiotics sometimes fail in such patients · Four scientists, in two teams, as they vied to be the first to create the right vaccine to prevent meningitis in infants In each of these deeply human stories, variables of chance, circumstance, and incorrect assumptions intervene to shape not just the arc of the scientists' lives, but the trajectory of how humans have come to understand one of our most pernicious diseases. Continual Raving is a mosaic tale of how science conquered meningitis -- and a larger story of the sometimes winding road to discovery.

Antimicrobial Resistance and Implications for the 21st Century

Antimicrobial Resistance and Implications for the 21st Century [Pdf/ePub] eBook ISBN-10: 0387724184
Author: I.W. Fong,Karl Drlica
Publisher: Springer Science & Business Media
File Size: 1450 KB
File Format: Pdf
Read Count: 5753822


Antimicrobial Resistance and Implications for the 21st Century by I.W. Fong,Karl Drlica Book Resume:

This comprehensive, up-to-date volume defines the issues and offers potential solutions to the challenges of antimicrobial resistance. The chapter authors are leading international experts on antimicrobial resistance among a variety of bacteria, viruses including HIV and herpes, parasites and fungi. The chapters explore the molecular mechanisms of drug resistance, the immunology and epidemiology of resistance strains, clinical implications and implications on research and lack thereof, and prevention and future directions.

Complications of Dialysis

Complications of Dialysis [Pdf/ePub] eBook ISBN-10: 0824745299
Author: Norbert Lameire,Ravindra Mehta
Publisher: CRC Press
File Size: 686 KB
File Format: Pdf
Read Count: 6940014


Complications of Dialysis by Norbert Lameire,Ravindra Mehta Book Resume:

Responding to the rising number of ESRD patients and the increasing importance of dialysis care and management, Complications of Dialysis provides a comprehensive, multidisciplinary perspective on the latest therapy options-addressing complications that may arise from dialysis and utilizing the patient-, technique-, and relationship-oriented approa

The Physician Assistant Student's Guide to the Clinical Year: Surgery

The Physician Assistant Student's Guide to the Clinical Year: Surgery [Pdf/ePub] eBook ISBN-10: 0826195342
Author: Brennan Bowker, MHS, PA-C
Publisher: Springer Publishing Company
File Size: 1232 KB
File Format: Pdf
Read Count: 4333239


The Physician Assistant Student's Guide to the Clinical Year: Surgery by Brennan Bowker, MHS, PA-C Book Resume:

“A lifesaver – not just for PA students, but for faculty and administrators trying our best to prepare them. Perfect for students to read and use on rotation.” – James Van Rhee, MS, PA-C, DFAAPA, Program Director, Yale Physician Assistant Online Program The first pocket-size resource to guide PA students through their surgery rotation Prepare for and thrive during your clinical rotations with the quick-access pocket guide series, The Physician Assistant Student’s Guide to the Clinical Year. The Surgery edition of this 7-volume series, discounted when purchased as a full set, delineates the exact duties required in this specialty. Written by an experienced PA educator, this guide details common surgical procedures you’ll see, such as thyroidectomy, hernia repair, mastectomy, and appendectomy. It also provides important information on surgical emergencies, including gastrointestinal bleeding, perforated viscus, and limb ischemia. System-based chapters reviewing the presentation and management of common conditions that may require surgery are also included. Advice on taking good SOAP notes, guidance on how to prepare patients for surgery, and tips on surgical etiquette will help you excel during this intense rotation. Additional chapters on pre- and post-operative management of patients, sterile technique, and common wound closure methods will arm you with the knowledge you’ll need to succeed. Key Features: Provides a pocket-size overview of the PA surgery rotation Describes common surgical procedures and emergencies Offers clinical pearls throughout Includes key abbreviations you’ll need to decipher in documentation Reflects the 2019 NCCPA PANCE blueprint Includes two bonus digital chapters! Three guided case studies to reinforce clinical reasoning plus 25 rotation exam-style questions with remediating rationales Other books in this series: The Physician Assistant Student’s Guide to the Clinical Year: Family Medicine Internal Medicine Emergency Medicine OB-GYN Pediatrics Behavioral Health

The Well-Cemented Total Hip Arthroplasty

The Well-Cemented Total Hip Arthroplasty [Pdf/ePub] eBook ISBN-10: 9783540289241
Author: Steffen Breusch,Henrik Malchau
Publisher: Springer Science & Business Media
File Size: 819 KB
File Format: Pdf
Read Count: 4254032


The Well-Cemented Total Hip Arthroplasty by Steffen Breusch,Henrik Malchau Book Resume:

Cemented Total Hip Arthroplasty (THA) remains one of the most successful procedures in Orthopaedic surgery. It has become very clear that it is the surgical expertise, in particular the quality of the cementing technique, which will affect long-term outcome and success. It is the intention of this book to provide an up-to-date comprehensive assessment of the entire field of cemented THA. Special emphasis has been given to practice-relevant aspects: well-illustrated and detailed operative steps as a practical guideline, a basic science chapter and long-term outcome data are provided. Minimally invasive surgery, modern perioperative management and patient fast tracking are covered. A number of highly respected experts have contributed to this in-depth compilation of the "state of the art" in 2005. This book is written and intended for both, trainees and established arthroplasty surgeons who are dedicated to perform a well-cemented THA.

Mad Cowboy

Mad Cowboy [Pdf/ePub] eBook ISBN-10: 0743219058
Author: Howard F. Lyman
Publisher: Simon and Schuster
File Size: 734 KB
File Format: Pdf
Read Count: 8999814


Mad Cowboy by Howard F. Lyman Book Resume:

Told by the man who kicked off the infamous lawsuit between Oprah and the cattlemen, Mad Cowboy is an impassioned account of the highly dangerous practices of the cattle and dairy industries. Howard Lyman's testimony on The Oprah Winfrey Show revealed the deadly impact of the livestock industry on our well-being. It not only led to Oprah's declaration that she'd never eat a burger again, it sent shock waves through a concerned and vulnerable public. A fourth-generation Montana rancher, Lyman investigated the use of chemicals in agriculture after developing a spinal tumor that nearly paralyzed him. Now a vegetarian, he blasts through the propaganda of beef and dairy interests—and the government agencies that protect them—to expose an animal-based diet as the primary cause of cancer, heart disease, and obesity in this country. He warns that the livestock industry is repeating the mistakes that led to Mad Cow disease in England while simultaneously causing serious damage to the environment. Persuasive, straightforward, and full of the down-home good humor and optimism of a son of the soil, Mad Cowboy is both an inspirational story of personal transformation and a convincing call to action for a plant-based diet—for the good of the planet and the health of us all.

The SAGE Encyclopedia of Pharmacology and Society

The SAGE Encyclopedia of Pharmacology and Society [Pdf/ePub] eBook ISBN-10: 1506301320
Author: Sarah E. Boslaugh
Publisher: SAGE Publications
File Size: 1217 KB
File Format: Pdf
Read Count: 3117333


The SAGE Encyclopedia of Pharmacology and Society by Sarah E. Boslaugh Book Resume:

The SAGE Encyclopedia of Pharmacology and Society explores the social and policy sides of the pharmaceutical industry and its pervasive influence in society. While many technical STM works explore the chemistry and biology of pharmacology and an equally large number of clinically oriented works focus on use of illegal drugs, substance abuse, and treatment, there is virtually nothing on the immensely huge business (“Big Pharma”) of creating, selling, consuming, and regulating legal drugs. With this new Encyclopedia, the topic of socioeconomic, business and consumer, and legal and ethical issues of the pharmaceutical industry in contemporary society around the world are addressed. Key Features: 800 signed articles, authored by prominent scholars, are arranged A-to-Z and published in a choice of electronic or print formats Although arranged A-to-Z, a Reader's Guide in the front matter groups articles by thematic areas Front matter also includes a Chronology highlighting significant developments in this field All articles conclude with Further Readings and Cross References to related articles Back matter includes an annotated Resource Guide to further research, a Glossary, Appendices (e.g., statistics on the amount and types of drugs prescribed, etc.), and a detailed Index The Index, Reader’s Guide, and Cross References combine for search-and-browse capabilities in the electronic edition The SAGE Encyclopedia of Pharmacology and Society is an authoritative and rigorous source addressing the pharmacology industry and how it influences society, making it a must-have reference for all academic libraries as a source for both students and researchers to utilize.

Is the End of the World Near?

Is the End of the World Near? [Pdf/ePub] eBook ISBN-10: 0761380477
Author: Ron Miller
Publisher: Twenty-First Century Books
File Size: 1289 KB
File Format: Pdf
Read Count: 7132610


Is the End of the World Near? by Ron Miller Book Resume:

At one time or another, just about everyone has talked about the end of the world. But what does this phrase really mean? Does it mean the end of the human race? The end of planet Earth? The end of our Sun and solar system? And if the world were to actually end, how and when would it happen? People have been asking these questions for thousands of years. Many religious prophets have predicted the end of the world. Science-fiction writers have created lots of end-of-the-world stories. Scientists, too, talk about natural events that could destroy human life or planet Earth. Some end-of-the-world events are dramatic. Imagine an asteroid slamming into Earth, creating a massive explosion. Other scenarios don't involve a single, catastrophic event. For example, global warming is changing the planet and threatening people, plants, and animals. It might not bring about the end of the world, but it might change life as we know it. In this book, we'll look at these scenarios and many more-everything from Mayan prophecy to nuclear disaster to the end of the universe. We'll find out which scenarios to ignore and which ones to really worry about.